apfcbAPFCB eNewscoAPFCB News Volume 2, Issue 2MultidisciplinaryEnglishJul-Dec, 2023NNY20240522ArticlesA New Horizon of Biochemistry and Laboratory Medicine with Chat GPTEnglishY7172KazuhikoKotani1EnglishN2EnglishY4 Pradeep KumarDabla3EnglishY4EnglishY10.62772/APFCB-News.2023.2.2Artificial intelligence (AI) is capable to simulate human intelligent behavior and critical thinking using computer and machine technology. At present, AI is transforming many fields of societies, including the medical field. One of the most recent topics in AI- based medicine is the Chat Generative Pre-trained Transformer, “ChatGPT” in brief, for generating human like text, which gives answers to queries in natural language processing. It led the world to the transformative potential of artificial intelligence (AI) with rare unexpected creativity. This is such a generative AI, and would be so helpful for building up knowledge and providing interpretations. It is part of the family of generative pre-training transformer (GPT) models that can engage with people to answer questions and uses natural language processing models. It is the largest publicly available language models in current state.Englishhttps://apfcb.org/APFCB_News/abstract?id=11References16191. The Lancet Digital Health. ChatGPT: Friend or foe? Lancet Digit Health. 2023; 5: E102.2. Ghosh A, Bir A. Evaluating ChatGPTand;rsquo;s stability to solve higher-order questions on the competency-based medical education curriculum in medical biochemistry. Cureus. 2023; 15: e37023.3. Cadamuro J, Cabitza F, Debeljak Z, De Bruyne S, Frans G, Perez SM, Ozdemir H, Tolios A, Carobene A, Padoan A. Potentials and pitfalls of ChatGPT and natural-language artificial intelligence models for the understanding of laboratory medicine test results. An assessment by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group on Artificial Intelligence (WG-AI). Clin Chem Lab Med. 2023; 61: 1158-1166.4. Gruson D, Dabla PK. Artificial intelligence and laboratory medicine: at the crossroads of value ethics and liability. APFCB News. 2023; 1: 69-70.5 . Cahan P, Treutlen B. A conversation with ChatGPT on the role of computational systems biology in stem cell research. Stem Cell Reports. 2023 Jan 10; 18(1):1