apfcbAPFCB eNewscoAPFCB News Volume 2, Issue 2MultidisciplinaryEnglishJul-Dec, 2023NNY20240522ArticlesQuality Control SystemsEnglishY6770Dr. TonyBadrick1EnglishN10.62772/APFCB-News.2023.2.1Laboratory results are a key enabler of disease diagnosis and the management of effective treatment. Therefore, clinical laboratories have a responsibility, often mandated, to provide results that are fit for those purposes. This means the assays must have stable characteristics and produce consistent results from day to day. Quality systems such as ISO 15189 have been produced by the international laboratory medicine community to provide a management and technical structure to assist laboratories in achieving these goals [1]. The Quality system includes governance processes, document control, equipment maintenance, staff training, and competence requirements to provide the essential supporting framework to build the capability needed to create and produce consistent results. However, the essential process that must be understood and utilised every day by most technical staff to produce patient results is the principles of quality control (QC).Englishhttps://apfcb.org/APFCB_News/abstract?id=10References16191. ISO 15189:2022 Medical laboratories and;mdash; Requirements for quality and competence, ISO. (2022).2. T. Badrick, The quality control system, Clin Biochem Rev. 29 Suppl 1 (2008) S67- 70.3. W.G. Miller, G.L. Myers, Commutability still matters, Clin Chem. 59 (2013) 1291and;ndash; 1293. https://doi.org/10.1373/clinchem.2013.208785.4. W.G. Miller, G.L. Myers, R. Rej, Why commutability matters, Clin Chem. 52 (2006) 553and;ndash;554. https://doi.org/10.1373/clinchem.2005.063511.5. P.M.S. Clark, L.J. Kricka, T.P. Whitehead, Matrix effects in clinical analysis: commutability of control materials between the Ketchum, Beckman and SMA 12 60 glucose and urea methods, Clinica Chimica Acta. 113 (1981) 293and;ndash;303. https://doi.org/10.1016/0009-8981(81)90282-5.6. J.O. Westgard, S.A. Westgard, Establishing evidence-based statistical quality control practices, Am J ClinPathol. 151 (2019) 364and;ndash;370. https://doi.org/10.1093/AJCP/AQY1587. J.O. Westgard, Statistical Quality Control Procedures, Clin Lab Med. 33 (2013) 111and;ndash;124. https://doi.org/10.1016/j.cll.2012.10.004.8. A. Katayev, J.K. Fleming, Past, present, and future of laboratory quality control: patient- based real-time quality control or when getting more quality at less cost is not wishful thinking, J Lab Precis Med. 5 (2020) 28and;ndash;28. https://doi.org/10.21037/jlpm-2019-qc-03.9. M. Panteghini, F. Ceriotti, G. Jones, W. Oosterhuis, M. Plebani, S. Sandberg, Strategies to define performance specifications in laboratory medicine: 3 years on from the Milan Strategic Conference, Clin Chem Lab Med. 55 (2017) 1849and;ndash; 1856. https://doi.org/10.1515/cclm-2017- 0772.10. P.J. Howanitz, G.A. Tetrault, S.J. Steindel, Clinical laboratory quality control: A costly process now out of control, Clinica Chimica Acta. 260 (1997) 163and;ndash;174. https://doi.org/10.1016/S0009- 8981(96)06494-7.11. G. Jones, J. Calleja, D. Chesher, C. Parvin, J. Yundt-Pacheco, M. Mackay, T. Badrick, Collective Opinion Paper on a 2013 AACB Workshop of Experts seeking Harmonisation of Approaches to Setting a Laboratory Quality Control Policy, Clin Biochem Rev. 36 (2015) 87and;ndash;95.12. H.H. van Rossum, A. Bietenbeck, M.A. Cervinski, A. Katayev, T.P. Loh, T.C. Badrick, Benefits, limitations and controversies on patient-based real-time quality control (PBRTQC) and the evidence behind the practice, Clin Chem Lab Med. 59 (2021) 1213and;ndash;1220. https://doi.org/10.1515/cclm-2021-0072.13. C.A. Parvin, A.M. Gronowski, Effect of analytical run length on quality-control (QC) performance and the QC planning process, Clin Chem. 43 (1997) 2149and;ndash;2154.14. T. Badrick, A.S. Brown, Identifying human factors as a source of error in laboratory quality control, J Lab Precis Med. (2023).15. C. Parvin, J. Jones, QC design: Itand;rsquo;s easier than you think. MLO. 2013; 45(12):18- 22. Medical Laboratory Observer. 45 (2013) 18and;ndash;22.16. C. Parvin, J. Jones, QC design: Itand;rsquo;s easier than you think. MLO. 2013; 45(12):18- 22. Medical Laboratory Observer. 45 (2013) 18and;ndash;22.