The enigma surrounding coffee-colored serum
Dr. Sailuja Maharjan, Dr. Sristi Upadhyay, Dr. Srinivas Chakravarthy
Dr. Sailuja Maharjan1 , Dr. Sristi Upadhyay 2 , Dr. Srinivas Chakravarthy3
1Department of Pathology, Kulhudhuffushi Regional Hospital, Kulhudhuffushi, Maldives
2Department of Pediatrics, Kulhudhuffushi Regional Hospital, Kulhudhuffushi, Maldives
3Department of Laboratory Medicine, Kauvery Hospital, Chennai, India
Corresponding Author:
Dr. Sailuja Maharjan,
Kulhudhuffushi Regional Hospital,
Kulhudhuffushi, Maldives.
Email: sailuzaa73@gmail.com
Abnormal discoloration of body fluids like serum or urine has been reported in the literature as a pharmacological adverse effect. Herein we report a patient with coffee-colored serum as an adverse effect of eltrombopag. Therefore, we alert the laboratory professionals and highlight the importance of visual inspection of the serum sample in a clinical laboratory and explore the possibilities. Furthermore, eltrombopag at high dose (200mg) can interfere with bilirubin assay based on the methodology used in the detection systems
